WISE CORTICAL STRIP

The WISE Cortical Strip (WCS) is a medical device for IntraOperative Neurophysiological Monitoring (IONM) during brain tumour and epilepsy surgeries.

The WCS is used for continuous recording of the brain’s spontaneous electrical activity (ECoG) and somatosensory evoked potentials (SEPs) and for brain stimulation, aimed to elicit motor evoked potentials (MEPs).

The WCS is manufactured with WISE’S proprietary and patented Supersonic Cluster Beam Implantation (SCBI). SCBI technology allows to produce devices with mechanical properties unattainable by conventional manufacturing processes in terms of thinness. Moreover, low and poorly disperse impedance values of the electrode have been confirmed in clinical settings.

Whereas traditional cortical strips are made of a stiff plate of stable shape, the WCS is composed of platinum electrodes embedded in a soft and thin film of silicone. The WCS is therefore highly ergonomic and conformable even on surfaces, such as the brain, with a floppy nature. These properties improve the adhesion and adaptability of the electrode’s contacts on the cortical surface.

WISE CORTICAL STRIP

Thanks to WISE’s innovative manufacturing technology, the WISE Cortical Strip allows extremely precise monitoring of the brain activity, featuring the following characteristics:
- highly ergonomic
- conformable
- soft and thin
- great adhesion
- excellent adaptability

WISE CORTICAL STRIP

Pre-clinical studies have confirmed the WCS functionality, performance, reliability, stability, biocompatibility, safety and usability, proving the device suitability for use in a clinical context for IntraOperative Neurophysiological Monitoring (IONM).

A European multicentric pre-market clinical study has confirmed the safety, performance and usability of WCS during surgical interventions.

The WCS is currently under evaluation for CE-marking purposes.

WISE CORTICAL STRIP

The WISE Cortical Strip (WCS) is a medical device for IntraOperative Neurophysiological Monitoring (IONM) during brain tumour and epilepsy surgeries.

The WCS is used for continuous recording of the brain’s spontaneous electrical activity (ECoG) and somatosensory evoked potentials (SEPs) and for brain stimulation, aimed to elicit motor evoked potentials (MEPs).

The WCS is manufactured with WISE’S proprietary and patented Supersonic Cluster Beam Implantation (SCBI). SCBI technology allows to produce devices with mechanical properties unattainable by conventional manufacturing processes in terms of thinness. Moreover, low and poorly disperse impedance values of the electrode have been confirmed in clinical settings.

Whereas traditional cortical strips are made of a stiff plate of stable shape, the WCS is composed of platinum electrodes embedded in a soft and thin film of silicone. The WCS is therefore highly ergonomic and conformable even on surfaces, such as the brain, with a floppy nature. These properties improve the adhesion and adaptability of the electrode’s contacts on the cortical surface.

SCS Expert lead

WISE is completing the development of the EXpandable PERcuTaneous lead for Spinal Cord Stimulation (SCS Expert). SCS Expert is the first multi-column SCS paddle lead for the treatment of chronic pain that can be implanted percutaneously by Pain Therapists.

Thanks to its proprietary and patented technology, WISE is the first company capable of producing a multicolumn paddle lead that can be folded in a catheter and implanted percutaneously like a cylindrical lead.

The SCS Expert combines the versatility, simple positioning and easy removal of percutaneous leads with the advantages of multicolumn paddle leads: directional stimulation and precise selection of the stimulation area.

The SCS Expert is not yet a legally marked device.

Other designs

WISE develops electrodes with applications on the Central Nervous System.

Thanks to its innovative SCBI technology, WISE is the first company that can produce leads for neuromonitoring and neurostimulation that are:
- Highly conformable
- Completely stretchable
- Minimally invasive

Due to the versatility of its technology, WISE can develop a broad range of electrodes for medical device systems, either implantable or non-implantable, both for acute and for chronic use.

WISE can realize any geometry of electrode arrays as well as contact shapes in various sizes, densities or grades of flexibility. The SCBI technology allows to produce medical devices with highly improved physicochemical properties regarding their strength, conformability and flexibility.